"NK cells in hypoxic skin mediate a trade-off between wound healing and antibacterial defence"

Acute wound healing is a highly coordinated cascade of different dynamic processes to ensure efficient repair of damaged tissue. The group of Prof. Christian Stockmann together with the research group of Prof. Lukas Sommer, and researchers in France, Austria, Japan, and Germany elucidated the fine balance between antimicrobial defence and rapid wound closure in skin. The Hypoxia-inducible transcription factor (HIF)-1α expressed in Natural Killer cells plays a key role in these new findings.

The open access publication can be found here: https://www.nature.com/articles/s41467-021-25065-w

More information to the topic can be found in the UZH press release.

Edda Kastenhuber